Friday, December 26, 2014

How Vaccine Formulation Development Assists In Modern Health Care

By Stacey Burt


The science of modern medicine may appear as sophisticated and technologically advanced to outside observers, and some techniques and pharmacological interventions lead to unstable outcomes or are difficult to forecast. Many patients are successfully treated by them. Yet there remain those illnesses which cannot be treated at all, and a significant proportion of the latter are the result of infection by what are known as viruses. The main imperative in approaching an untreatable virus is vaccine formulation development.

Unlike other pathogens, a virus cannot be destroyed by an antibiotic, since, technically it is not alive (i. E. Biotic in nature). Also, it is a germ, so it cannot be eliminated through mechanical techniques such as surgery or ultrasound. The only effective known intervention is a vaccine.

A vaccine partially imitates the virus in the patient's body, so that the person's immune system starts to manufacture viral antibodies. The body does this in response to the detected threat of the pseudo-virus (the vaccine).

These antibodies are the natural reaction to the viral infection. The immune system manufactures them in response to the virus' presence, and only the human body is able to do this. After the infection has been eliminated, the antibodies remain in the system, preventing relapses for the rest of the person's life. This is why vaccination has the potential to bring about permanent resistance (or immunity) to a specific virus.

This permanent resistance is the reason why young kids are vaccinated against certain obvious, common diseases, such as polio or measles. Once immunized, people remain safe fort he rest of their lives, since the antibodies are always present. Even extremely mundane, seemingly innocuous illnesses, such as smallpox, were immense threats to public health in the past and the introduction of effective vaccines was the main step in removing them from society.

Some of the most lethal or serious sicknesses are the result of viral activity. The hemorrhagic fever Ebola is one, as is AIDS, meningitis (in one of its forms), and, as mentioned in the preceding paragraph, polio (which paralyses the patient if left untreated). Targeting these viruses for immunization development is obviously a primary priority in modern medicine. The public recognizes this priority, and the media are not slow to report on attempts to formulate an antidote to a notorious disease, no matter how empty such attempts may turn out to be.

Over time, however, a virus may mutate and return to a medication-resistant state. It either mutates into a new genetic form (strain), or simply develops resistance against the patient's antibodies. As frightening as this may sound, it is an ongoing phenomenon, as seen, for example, in the case of the influenza virus, which presents in a new strain every year. There is no immunization process against it because it mutates too quickly.

Ultimately, people should realize that a vaccine is only part of the solution to public infection and epidemics. If they are to be safe, people should also try to exercise sound personal health habits. Many illnesses, such as AIDS, can be prevented through basic practical precautions, and relying on science to produce cures is not always an option or even sensible.




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